The band, led by Bright Eyes frontman Connor Oberst, have had to pull out of the tour due to "an issue of personal nature", said Soundwave promoter AJ Maddah, who confirmed the news on Twitter overnight.
Desaparecidos have had to postpone their Australian trip due to an issue of personal nature. #SW14— AJ (@iamnotshouting) February 17, 2014
As we are waiting on official announcement I can't really go into it except to offer my support & love to my friend Conor at this time #SW14— AJ (@iamnotshouting) February 17, 2014
Desaparecidos were meant to visit Australia last November for the Harvest Festival, which was cancelled.
In recent weeks, Whitechapel, Megadeth, Stone Temple Pilots and Sevendust have each cancelled their appearances for Soundwave.
This week's new sets include local acts Born Lion, The Getaway Plan, Morning Harvey, Fraser A Gorman and more.